This policy setting defines the number of days items should be kept in the Quarantine folder before being removed. If you enable this setting items will be removed from the Quarantine folder after the number of days specified. If you disable or do not configure this setting items will be kept in the quarantine folder indefinitely and will not be automatically removed.
Configure removal of items from Quarantine folder
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HKEY_LOCAL_MACHINE -> Software -> Policies -> Microsoft -> Windows Defender -> Quarantine # PurgeItemsAfterDelay; HKEY_LOCAL_MACHINE -> Software -> Policies -> Microsoft -> Windows Defender -> Quarantine # PurgeItemsAfterDelay
Windows Components -> Windows Defender -> Quarantine